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Application of Stress Hormones in Saliva in Research of Orofacial Pain Related with Stress

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À¯Áö¿ø, À±Ã¢·ú, ¾ÈÁ¾¸ð,
¼Ò¼Ó »ó¼¼Á¤º¸
À¯Áö¿ø ( Ryu Ji-Won ) - Á¶¼±´ëÇб³ Ä¡°ú´ëÇÐ ±¸°­³»°úÇб³½Ç
À±Ã¢·ú ( Yoon Chang-Lyuk ) - Á¶¼±´ëÇб³ Ä¡°ú´ëÇÐ ±¸°­³»°úÇб³½Ç
¾ÈÁ¾¸ð ( Ahn Jong-Mo ) - Á¶¼±´ëÇб³ Ä¡°ú´ëÇÐ ±¸°­³»°úÇб³½Ç

Abstract

¸¹Àº Áúº´µé°ú ±âÁ¸¿¡ Á¸ÀçÇÏ´Â ½ÅüÀûÀÎ Áúº´µéÀº ½ºÆ®·¹½º·Î ÀÎÇØ ¹ßº´µÇ°Å³ª Å©°í ÀÛÀº ½ºÆ®·¹½ºÀÇ ¿µÇâÀ¸·Î ¾ÇÈ­µÈ´Ù. ½ºÆ®·¹½ºÀÇ ¿¬±¸¿¡ È£¸£¸óÀ» »ç¿ëÇÏ´Â ±âº»Àº ½ÅüÀÇ ´ëºÎºÐ ½Ã½ºÅÛÀÌ ½ºÆ®·¹½º¸¦ ¹Þ´Â µ¿¾È º¯È­¸¦ º¸Àδٴ °Í°ú ÀÌ·¯ÇÑ º¯È­¿¡ È£¸£¸óÀÌ ½ºÆ®·¹½º¿Í È®½ÇÇÏ°Ô ¿¬°üµÇ¾î ÀÖ´Ù´Â °ÍÀ» °üÂûÇÏ´Â °ÍÀÌ´Ù. °³³äÀûÀ¸·Î ½ºÆ®·¹½º¿¡ À־ ±³°¨½Å °æ°è¿Í ½Ã»óÇϺÎ-³úÇϼöü-ºÎ½ÅÃàÀÇ È°¼ºÈ­°¡ Áß½ÉÀûÀÎ ¿ªÇÒÀ» ÇÑ´Ù´Â °ÍÀÌ È£¸£¸óÀÇ º¯È­¸¦ ÃøÁ¤ÇØ¾ß ÇÒ ÃæºÐÇÑ ±Ù°Å¸¦ Á¦°øÇÑ´Ù. ¿¡Çdz×ÇÁ¸°°ú ³ë¸£¿¡Çdz×ÇÁ¸°°ú °°Àº Ä«Å×Äݶó¹Î, ÄÚƼÁ¹, Å×½ºÅ佺Å×·Ð ±×¸®°í ¼ºÀåÈ£¸£¸ó µîÀº ½ºÆ®·¹½º¿¡ ¿¹¹ÎÇÑ ¹ÝÀÀÀ» º¸ÀδÙ. ÇÑÆí ½ºÆ®·¹½º ¿¬±¸¸¦ À§ÇÑ Å¸¾×Ç¥º»Àº Ç÷¾×À̳ª ¿äÀÇ Ç¥º»°ú´Â ´Þ¸® ½ºÆ®·¹½º¸¦ ÁÖÁö ¾Ê°íµµ Ç¥º»À» ¾òÀ» ¼ö ÀÖÀ¸¸ç ½ÅüÀûÀÎ ±¸¼ÓÀ̳ª À±¸®ÀûÀÎ ¹®Á¦ µîÀ» ¿°·ÁÇÏÁö ¾Ê°íµµ äÃë°¡ °¡´ÉÇÏ´Ù´Â ÀåÁ¡ÀÌ ÀÖ´Ù. Ÿ¾×³»ÀÇ È£¸£¸óÀÇ ¼öÄ¡´Â Ç÷¾×³»ÀÇ È£¸£¸ó ¼öÄ¡¸¦ Àß ¹Ý¿µÇϹǷΠ½ºÆ®·¹½º¿Í °ü·ÃµÈ ±¸°­¾È¸éÅëÁõÀÇ ¿¬±¸¿¡ À־ Ÿ¾×³»ÀÇ ½ºÆ®·¹½º È£¸£¸ó¿¡ È°¿ëµµ´Â ¸Å¿ì ³ôÀ¸¸®¶ó°í »ç·áµÈ´Ù.

Many diseases occur by stress or effect of stress. The basis for using hormones in research of stress is the observation that most systems in the body show changes during stress and that hormonal markers in these changes are related with stress. Conceptually, the central role of sympathetic nervous system(SNS) and hypothalamus-pituitary-adrenal(HPA) axis activity in stress provides copious justification for measuring hormonal changes. Catecholamines like epinephrine and norepinephrine, cortisol, testosterone and growth hormone and so on show sensitive reaction to stress. The major advantage of salivary sample to stress research is that its sampling technique can be performed in non-stressful conditions and without physical restraint and ethical problems. Because hormone levels in saliva is a good reflection of hormone levels in plasma, application of stress hormones in saliva is very useful for research of orofacial pain related with stress.

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Stress;Hormone;Saliva;Orofacial pain

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